中药药性理论是中药基本理论研究的重点和难点,药性概念、构成及表征的复杂性长期困扰着研究人员,亟需研究视角和方法的创新。从认知科学角度看,中药药性理论的产生就是人们在与疾病斗争的医疗实践中面对中药及其作用的感官信息,在中国传统哲学思维指导下进行储存、提取、重建、总结,进而形成有关药物疗效性质概念的认知学过程;中药药性认知过程具有其特殊的认知要素和认知策略。本研究遵循中药临床应用特点,明晰其特殊认识要素,结合现代化学、生物学、数学研究手段,在本室5年前期工作基础上,构建基于“三要素”的中药药性认知模式,并以辛热药为示例进行实践,以期实现传统中药药性的现代科学解读,为阐明药性本质提供思考,为临床合理用药提供指导。 The theory of TCM medicinal properties is the key and difficult point in the study of the basic theory of traditional Chinese medicine. The complexity, concept, composition and characterization of medicinal properties has plagued researchers for so long, and it is urgent to study the innovation of perspectives and methods. From the cognitive science point of view, the emergence of Chinese medicinal theory is the sensory information that people face Chinese medicine and its role in the medical practice of struggling with the disease. It is stored, extracted, reconstructed and summarized under the guidance of Chinese traditional philosophical thinking and then formed The cognitive process of the concept of drug efficacy properties; the process of TCM cognition has its own special cognitive elements and cognitive strategies. Based on the characteristics of clinical application of traditional Chinese medicine, this study clarified the special cognitive elements of traditional Chinese medicine. Based on the modern chemistry, biology and mathematical research methods, based on the previous work five years ago, this study constructed a cognitive model of traditional Chinese medicine based on “three elements” In order to realize the modern scientific interpretation of the traditional Chinese medicine’s medicinal properties, the practice is to take Xinmayao as an example to provide thinking for elucidating the nature of medicinal properties and to provide guidance for clinical rational use of medicines.