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目的探讨脑干听觉诱发电位(BAEP)在高血压病2级、3级与脑干梗死之间的变化规律及相应的病理生理改变。方法将110例患者按高血压病2、3级(符合世界卫生组织规定的标准)及临床确诊的脑干梗死分为三组,均行BAEP和颅脑影像学检查,三组患者的性别和年龄无显著性差异,具有可比性。BAEP改变按轻、中、重分析统计。结果脑干梗死组、高血压病3级组、高血压病2级组BAEP重度异常率分别为52%、30%、3%;轻度异常率分别为40%、57%、53%;正常率为8%、13%、43%;三组之间BAEP有显著性差异;组间比较:脑干梗死组与高血压病2级组、高血压病3级与2级组间有显著性差异;脑干梗死组与高血压病3级组之间无显著性差异。结论BAEP可及早发现高血压病患者临床下脑干病变,应及早进行干预治疗,防止病变进一步发展;同时,BAEP也能对脑干梗死患者的预后提供客观的临床证据。
Objective To investigate the changes of brainstem auditory evoked potential (BAEP) between hypertensive patients with grade 2 and 3 and infarction of brain stem and the corresponding pathophysiological changes. Methods One hundred and ten patients were divided into three groups according to Hypertension Grade 2 and Grade 3 (in line with the standards prescribed by the World Health Organization) and clinically diagnosed brainstem infarction. All patients underwent BAEP and brain imaging examination. The sex and No significant difference in age, comparable. BAEP change by light, medium and heavy analysis of statistics. Results The severe abnormal BAEP rate was 52%, 30% and 3% in the infarction group, the third grade of hypertension and the second grade of hypertension. The mild abnormal rates were 40%, 57% and 53% Rates were 8%, 13%, 43%; BAEP between the three groups were significantly different; between groups: brain stem infarction group and hypertensive grade 2 group, hypertensive grade 3 and 2 were significant There was no significant difference between the infarction group and the third grade group of hypertension. Conclusions BAEP can detect clinical sub-brainstem lesions in patients with hypertension early and should be intervened as early as possible to prevent further development of the disease. Meanwhile, BAEP can also provide objective clinical evidence for the prognosis of patients with brainstem infarction.