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Ｃ＿（５７）ＢＬ／６小鼠经小剂量Ｘ射线（１．２５ｍＧｙ／ｍｉｎ）全身照射６分钟，２４小时后取其脾细胞及未受照射鼠脾细胞分别与Ｌｅｗｉｓ肺癌细胞（ＬＬＣ）按比例混合注入两组Ｃ＿（５７）ＢＬ／６小鼠足掌，定期测量足掌肿瘤生长时发现：混有受照鼠脾细胞的ＬＬＣ生长及自发肺转移明显低于混合未受照鼠脾细胞的对照组（Ｐ＜０．０５）。体外实验发现，受照鼠脾细胞经ＣｏｎＡ刺激后转化能力明显提高，且ＮＫ细胞活性明显高于对照组（Ｐ＜０．０１），提示低剂量Ｘ线照射使小鼠Ｔ细胞功能，ＮＫ细胞功能增强来抑制肿瘤生长和转移。
C57BL / 6 mice were exposed to low dose X-ray (1.25mGy / min) for 6 minutes. After 24 hours, their splenocytes and non-irradiated mouse spleen cells were counted with Lewis lung carcinoma cells (LLC) Mixed injection of two groups of C57BL / 6 mouse paw, regular measurement of foot palm tumor growth found: mixed with irradiated spleen cells LLC growth and spontaneous lung metastasis was significantly lower than the mixed non-irradiated mouse spleen cells Control group (P <0.05). In vitro experiments showed that the ability of splenocytes stimulated by ConA after transfection was significantly increased, and the activity of NK cells was significantly higher than that of the control group (P <0.01), suggesting that low dose of X-ray irradiation can improve the function of T cells, NK cells Enhanced function to inhibit tumor growth and metastasis.