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目的评估慢性肾功能衰竭(chronic renal failure,CRF)患者并胃食管病(GRED)的临床特点。方法分为实验组:选取2004.7-2012.2年期间单纯慢性肾病并慢性肾功能衰竭,一般情况良好,血压及贫血控制基本正常,透析充分的患者154例;对照组:我院职工随机选取360例(经常规体检无基础疾病的)。采用胃食管反流诊断问卷(RDQ)及胃镜评估其胃食管反流病的发生率及临床症状特点。结果两则相比实验组发病率明显高于对照组(P<0.01),食管炎发病率高(P<0.05),症状突出(P<0.05)。结论实验组患者更加容易出现胃食管反流病,同时症状明显,也是导致此类患者生活质量下降的重要原因之一。
Objective To evaluate the clinical features of patients with chronic renal failure (CRF) and gastroesophageal disease (GRED). Methods were divided into experimental group: selected from 2004.7 - 2012.2 years of simple chronic kidney disease and chronic renal failure, the general situation is good, control of blood pressure and anemia was normal, fully dialysis patients 154 cases; control group: Routine physical examination without underlying diseases). Gastroesophageal reflux diagnostic questionnaire (RDQ) and gastroscopy were used to evaluate the incidence of gastroesophageal reflux disease and clinical features. Results The incidence of esophagitis in both groups was significantly higher than that in the control group (P <0.01). The incidence of esophagitis was higher (P <0.05) and the symptoms were prominent (P <0.05). Conclusions Patients in the experimental group are more prone to gastroesophageal reflux disease with obvious symptoms and also one of the important reasons leading to the decline of the quality of life of these patients.