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目的初步探讨相位校正多回波GRE Dixon序列在原发性肝癌诊断中的作用。材料与方法利用GRE Dixon序列扫描22例原发性肝癌患者,分析其在GRE Dixon序列生成的水像、脂像、水/脂相位图、R2*像的影像特点,并与传统T1、T2像及病理结果对照。结果胆管细胞癌与含脂肝细胞癌在水像上大多呈低信号,不含脂的肝细胞癌在水像上大多呈等信号。多数肿瘤中的出血、坏死在R2*像能够显示,优于T2像。胆管细胞癌的R2*值低于肝细胞癌(P=0.003)。R2*像中肿瘤与肝组织的对比噪声比低于T2像。结论分析相位校正多回波GRE Dixon的图像能够判断肝脏肿瘤组织内的出血、坏死、脂变、纤维成份,有利于胆管细胞癌与肝细胞癌的鉴别。
Objective To investigate the role of phase-corrected multi-echo GRE Dixon sequence in the diagnosis of primary liver cancer. MATERIALS AND METHODS: Twenty-two patients with primary hepatocellular carcinoma were screened by GRE Dixon sequence. The characteristics of water, lipids, water / fat phase maps and R2 * images generated by the GRE Dixon sequence were analyzed. Compared with the conventional T1 and T2 images And pathological results of control. Results cholangiocarcinoma and fat-containing hepatocellular carcinoma mostly showed low signal on the watery image, and most of the hepatocellular carcinoma without fat appeared equal signals on water. In most tumors, hemorrhage and necrosis in R2 * images can show better than T2 images. The R2 * value of cholangiocarcinoma was lower than that of hepatocellular carcinoma (P = 0.003). R2 * like tumor and liver tissue contrast ratio lower than the T2 image. Conclusions Analysis of phase-corrected multi-echo images of GRE Dixon can determine the hemorrhage, necrosis, lipid alteration and fibrosis in hepatic tumor tissues, which is beneficial to the identification of cholangiocarcinoma and hepatocellular carcinoma.