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用一种未见文献报道的简便方法,将侧链羟基不保护的苏氨酸,丝氨酸还原制备了苏氨醇,丝氨醇。并用新型的有机磷缩合试剂DEPBT成功地合成了C端为苏氨醇,丝氨醇的二肽醇和四肽醇。
In a simple way that has not been reported in the literature, threonine and serinol were prepared by reducing the threonine and serine which are not protected by the side chain hydroxyl groups. And with a new type of organic phosphorus condensation reagent DEPBT successfully C-terminal for threonine, serin diol and tetrapeptide alcohols.