背景与目的:研究仙人掌原液的毒性。材料与方法:小鼠急性毒性试验、Ames试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验、大鼠30 d喂养试验。结果:仙人掌原液雌、雄小鼠LD50均大于20.0 g／kg,属无毒物质;Ames试验、微核试验和精子畸形试验结果均为阴性;大鼠30 d喂养试验结果显示该样品30 d喂养对大鼠各项观察指标未见毒性作用。结论:在本次实验条件下,仙人掌原液为无毒物质,未显示有遗传毒性和亚急性毒性作用。 Background and purpose: To study the toxicity of cactus stock solution. Materials and Methods: Mouse acute toxicity test, Ames test, micronucleus test of mouse bone marrow polychromatic erythrocytes, mouse sperm abnormality test, 30-day feeding test of rats. Results: The LD50 of male and female mice of cactus stock was more than 20.0 g/kg, which was non-toxic substance. The results of Ames test, micronucleus test and sperm abnormality test were all negative. The results of 30 d feeding test showed that the sample was fed for 30 days. No toxic effects were observed on the various indicators of the rat. Conclusion: Under the conditions of this experiment, the cactus stock solution was non-toxic and did not show genotoxicity and sub-acute toxicity.