活动性十二指肠溃疡经治疗痊愈后,复发率相当高。作者通过对140例十二指肠溃疡已愈病人进行2年随机双盲研究,以了解雷尼替丁维持治疗预防十二指肠溃疡复发的作用。方法:140例病人被随机分为维持治疗组(70例),每晚服雷尼替丁150毫克。安慰剂组(70例),每晚服与雷尼替丁外观完全相同的安慰剂。疼痛和消化不 Active duodenal ulcer after treatment recovered, the recurrence rate is quite high. The authors studied 140 patients with duodenal ulcer who had been cured by a two-year randomized double-blind study to understand the role of ranitidine maintenance treatment to prevent the recurrence of duodenal ulcer. Methods: One hundred and forty patients were randomized to maintenance therapy (n = 70) and ranitidine 150 mg per night. Placebo (n = 70) received the same placebo as ranitidine every night. Pain and digestion do not