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目的:研究新辅助治疗在局部晚期结直肠癌治疗中的价值。方法:选取广州医科大学第二附属医院收治的直肠癌晚期患者80例作随机分组,对照组直接行手术治疗,新辅助组患者则使用新辅助治疗方法,比较两组患者的治疗总有效率。结果:对照组患者的治疗总有效率为75.00%,新辅助组的治疗总有效率为90.00%,组间比较,差异具有统计学意义(P<0.05)。新辅助组患者均完全耐受新辅助治疗,无1例患者退出,退出率为0。在完成治疗之后,经过检查,新辅助组患者的肿瘤与治疗之前比较有明显缩小。结论:使用新辅助治疗对局部晚期结直肠癌患者有显著的临床效果。
Objective: To study the value of neoadjuvant therapy in the treatment of locally advanced colorectal cancer. Methods: Eighty patients with advanced rectal cancer who were admitted to the Second Affiliated Hospital of Guangzhou Medical University were randomly divided into two groups: the control group received surgery directly; the neoadjuvant group received neoadjuvant therapy; and the total effective rate was compared between the two groups. Results: The total effective rate was 75.00% in the control group and 90.00% in the neoadjuvant group. The difference between the two groups was statistically significant (P <0.05). Neoadjuvant patients were completely tolerated neoadjuvant therapy, no patient withdrawal, the withdrawal rate of 0. After the completion of treatment, after examination, the neoadjuvant patients with tumors were significantly reduced compared with before treatment. Conclusion: The use of neoadjuvant therapy in patients with locally advanced colorectal cancer have a significant clinical effect.