论文部分内容阅读
目的分析不合理使用抗菌药物致不良反应的原因,并制订应对策略以提高临床用药的合理性。方法选取2012年12月至2015年1月由鹿邑真源医院提供的药物不良反应案例150例,所有患者均因抗菌药物不合理所致。统计150例患者使用抗菌药物种类、不合理用药原因、不良反应发生情况及累及系统、器官。结果 150例患者中,头孢类抗菌药物使用率最高,其次为青霉素类和克林霉素类;不合理使用抗菌药物的主要原因为给药时间过长和滴速过快,其次为药液浓度过高;150例不合理使用抗菌药物患者中,121例出现显著不良反应,占80.7%;其中,不良反应主要累及部位为皮肤,其次为消化系统。结论通过对不合理使用抗菌药物致不良反应的原因进行分析,可以为临床合理用药提供有效指导。同时,应采取有效措施进行处理,以尽可能地减少不良反应的发生。
Objective To analyze the causes of adverse reactions caused by irrational use of antimicrobial agents and to develop strategies to improve the rationality of clinical medication. Methods A total of 150 cases of adverse drug reactions were provided from Luyi Zhenyuan Hospital from December 2012 to January 2015, all of which were caused by unreasonable antibacterial drugs. Statistics of 150 patients using antibacterial drugs, irrational drug use, adverse reactions and involving the system, organs. Results Among the 150 patients, the highest use rate of cephalosporins was penicillins and clindamycins. The main reasons for the unreasonable use of antibacterials were excessive administration time and rapid drip rate, followed by liquid drug concentration Too high; 150 cases of unreasonable use of antibiotics in patients, 121 cases showed significant adverse reactions, accounting for 80.7%; of which, the main adverse reactions involving the skin, followed by the digestive system. Conclusion Through the analysis of the causes of adverse reactions caused by unreasonable use of antibacterial drugs, it can provide effective guidance for clinical rational drug use. At the same time, effective measures should be taken to deal with, in order to minimize the occurrence of adverse reactions.