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目的探讨米索前列醇在预防产妇产后出血中的应用效果及其安全性。方法选取福建医科大学附属龙岩第一医院产科2015年6月—2016年6月收治的经阴道分娩产妇120例,根据简单数字表法分为对照组和试验组,各60例。对照组产妇给予宫缩素治疗,试验组产妇给予米索前列醇治疗。统计比较两组产妇产后出血发生率及产后2 h、24 h出血量,并观察两组产妇不良反应发生情况。结果试验组产妇产后出血发生率低于对照组(P<0.05)。试验组产妇产后2 h、24 h出血量均少于对照组(P<0.05)。试验组产妇不良反应发生率低于对照组(P<0.05)。结论米索前列醇在预防产妇产后出血中的应用效果确切,可有效减少产后出血量,且安全性高。
Objective To investigate the effect and safety of misoprostol in preventing postpartum hemorrhage. Methods A total of 120 cases of vaginal delivery were collected from June 2015 to June 2016 in Longyan First Hospital Affiliated to Fujian Medical University and divided into control group and experimental group according to the simple digital table method. The control group maternal treatment of orifices, test group maternal misoprostol treatment. The incidence of postpartum hemorrhage and postpartum 2 h and 24 h postoperative bleeding were statistically compared between the two groups and the occurrence of adverse reactions in the two groups were observed. Results The incidence of postpartum hemorrhage in the experimental group was lower than that in the control group (P <0.05). The amount of bleeding in the experimental group at 2 h and 24 h postpartum was less than that in the control group (P <0.05). The incidence of maternal adverse reactions in the experimental group was lower than that in the control group (P <0.05). Conclusion Misoprostol in the prevention of postpartum hemorrhage in the application of the exact effect, can effectively reduce the amount of postpartum hemorrhage, and high safety.