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目的探讨介入治疗在中晚期胃癌患者的治疗效果及耐受性。方法介入组(治疗组)30例患者行股动脉穿刺插管,腹腔动脉造影,确定位置,向靶血管内注入化疗药物及栓塞剂的治疗,并与静脉化疗组(对照组)20例进行效果及毒副反应比较。结果治疗组有效率高于对照组,治疗组中腹痛、腹胀及进食梗噎缓解改善的更为明显,与对照组比较差异有统计学意义。两组间比较恶心、呕吐及白细胞下降差异有统计学意义,对照组重于治疗组。结论动脉介入化疗不仅有较高的局部缓解率,而且毒副反应轻,患者的耐受性及依从性好,提高了患者的生活质量,是治疗中晚期胃癌的一种新方法。
Objective To investigate the therapeutic effect and tolerability of interventional therapy in patients with advanced gastric cancer. Methods Thirty patients undergoing interventional therapy (intervention group) underwent femoral arterial puncture, celiac angiography, site-specific injection of chemotherapeutic agents and embolization agents into the target vessel, and 20 patients treated with intravenous chemotherapy (control group) And toxicity comparison. Results The effective rate of the treatment group was higher than that of the control group. In the treatment group, it was more obvious that the abdominal pain, abdominal distension and eating stool were relieved and alleviated. The difference was statistically significant compared with the control group. The two groups were more nausea, vomiting and leukopenia difference was statistically significant, the control group was heavier than the treatment group. Conclusion Arterial intervention chemotherapy not only has high local remission rate, but also mild side effects, patient tolerance and compliance, improve the quality of life of patients, is a new method of treatment of advanced gastric cancer.