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目的研究以卡托普利为代表的ACEI制剂对高血压患者血糖、血脂代谢的影响。方法采用治疗前后自身对照试验法,分别测定36例原发性高血压患者治疗前、后的空腹血糖、CHO、TG、HDLC、血压等指标。结果用药后SBP、DBP均有显著下降(P<0.005),空腹血糖、血脂无明显变化(P>0.05)。结论ACEI制剂可有效降压,且对血糖、血脂无不良影响。
Objective To investigate the effects of ACEI, represented by captopril, on blood glucose and lipid metabolism in hypertensive patients. Methods Before and after treatment with self-control test, 36 cases of essential hypertension were measured before and after treatment, fasting blood glucose, CHO, TG, HDLC, blood pressure and other indicators. Results SBP and DBP decreased significantly after treatment (P <0.005), while no significant changes in fasting blood glucose and blood lipid (P> 0.05). Conclusion ACEI preparations can be effectively depressurized, and no adverse effects on blood glucose and blood lipids.