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目的观察高频振荡通气对小儿急性呼吸窘迫综合征(ARDS)的疗效和安全性。方法 65例在本院PICU治疗的ARDS患儿,随机分成两组,治疗组33例采用高频振荡通气,对照组32例采用常频机械通气,观察两组的氧合指数、通气时间、住院时间及并发症。结果治疗组在2、15、24 h不同时间点氧合指数(OI)改善明显优于对照组,差异有统计学意义(P<0.05)。通气时间、住院时间明显低于对照组,差异有统计学意义(P<0.05),并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论高频振荡通气临床疗效明显、安全,值得推广。
Objective To observe the efficacy and safety of high frequency oscillatory ventilation in children with acute respiratory distress syndrome (ARDS). Methods A total of 65 ARDS children treated with PICU in our hospital were randomly divided into two groups. 33 cases in the treatment group were treated by high-frequency oscillatory ventilation and 32 cases in the control group were treated by normal-frequency mechanical ventilation. The oxygenation index, ventilation time, Time and complications. Results The improvement of oxygenation index (OI) of the treatment group at 2, 15 and 24 h was significantly better than that of the control group (P <0.05). Ventilation time and hospitalization time were significantly lower than the control group, the difference was statistically significant (P <0.05), the incidence of complications was lower than the control group, the difference was statistically significant (P <0.05). Conclusions The clinical effect of high-frequency oscillatory ventilation is obvious, safe and worthy of promotion.