论文部分内容阅读
大部份水溶性β-内酰胺抗生素由于口服生物利用度低而采用静注或肌注给药,肌注因局部副作用且药物在直肠和小肠内吸收差,故试用肽胶原N-乙酰基衍生物作提高氨苄青霉素钠在兔和大鼠内药物吸收试验
Most water-soluble β-lactam antibiotics due to low oral bioavailability by intravenous or intramuscular injection, intramuscular injection due to local side effects and drugs in the rectum and small intestine absorption is poor, so the experimental peptide collagen N-acetyl derivative Creature enhances ampicillin sodium in rabbits and rats drug absorption test