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血吸虫生活史各阶段可作为血吸虫疫苗和药物介入的靶阶段。对血吸虫不同发育阶段蛋白分子和基因表达的动态变化的了解 ,有助于探索其生长发育的机制 ,为研制有效的阻断传播的疫苗和新的药物提供科学指导。本文就血吸虫受发育调节而呈阶段性表达的蛋白及其功能方面进行综述
The stages of schistosomiasis life history can be used as the target stage of schistosome vaccine and drug intervention. The understanding of the dynamic changes of protein molecules and gene expression at different developmental stages of Schistosoma japonicum helps to explore the mechanism of its growth and development and provide scientific guidance for the development of effective vaccines and new drugs that block the transmission. In this paper, the development and regulation of schistosomiasis was staged expression of proteins and their functions were reviewed