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CD８１是一种跨膜的非糖基化蛋白。在人类和黑猩猩中，CD８１胞外区EC２区氨基酸序列高度保守。CD８１可影响细胞的粘附、激活、增殖和分化，改变细胞形态及抑制合胞体形成等生物学功能〔１〕。近年研究发现，CD８１可能作为HCV的受体引导病毒进入细胞内〔２〕。进一步研究发现
CD81 is a transmembrane, non-glycosylated protein. In humans and chimpanzees, the extracellular region of CD81 has a highly conserved amino acid sequence in the EC2 region. CD81 can affect cell adhesion, activation, proliferation and differentiation, changes in cell morphology and inhibition of syncytia formation and other biological functions 〔1〕. Recent studies found that CD81 may act as a HCV receptor to guide the virus into the cell 〔2〕. Further research found