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我院以中国人民解放军302医院制备的戊型肝炎诊断试剂固相捕获IgMELISA直接法检测抗HEV-IgM及竞争法检测抗-HEV总抗体作为戊型肝炎病原学诊断依据,1992年3～5月入院治疗的肝炎患者中发现有42例阳性,男性占81％(34例),中老年多发,平均年龄49岁,没有20岁以下的青少年病例,以市内散发为特点,均无家庭聚集及继发现象;所有病例均无外地旅游史,否认饮用生水,除1例因剖腹产有输血史外其余病人均无输血或血制品史,排除肝炎病人密切接触史;但共有38人(90.5％)有不同程度的在外饮食习惯,这些病人可能与外出不洁饮食有关,但明确的感染来源尚不清楚;临床均为急性起病过程,尤以急性黄疸型为主,占85.7％(36例),且呈自限性经过,经临床常规护肝治疗,所有患者预后良好,无一例死亡。
Our hospital to the Chinese People’s Liberation Army 302 Hospital preparation of hepatitis E diagnostic reagent solid phase capture IgMELISA direct detection of anti-HEV-IgM and competition assay of anti-HEV total antibody as hepatitis E etiological diagnosis based on March 1992 to May Forty-two patients were found to be hospitalized and 81% (34%) were male. The average age was 49 years. There were no cases of adolescents under 20 years of age. They were characterized by domestic distribution and no family aggregation All cases had no history of foreign travel, and denied drinking raw water. All patients except one had history of blood transfusion or blood product due to blood transfusion during caesarean section, and had close contact with hepatitis patients. However, 38 (90.5% ) Have different degrees of eating habits, these patients may be related to eating unclean diet, but a clear source of infection is not clear; clinical onset of acute onset, especially acute jaundice, accounting for 85.7% (36 cases ), And was self-limiting after the clinical routine liver protection, all patients with good prognosis, without a single death.