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目的分析东台市2007—2011年出生缺陷监测资料,为进一步降低出生缺陷发生率,探讨切实可行的干预措施提供依据。方法按照全国出生缺陷监测方案要求,对东台市2007—2011年29家监测医院住院分娩的围产儿进行监测。结果监测34 498例围产儿中,出生缺陷儿148例,出生缺陷发生率为4.29‰。5年出生缺陷率差异无统计学意义(P>0.05)。前5位出生缺陷依次为:肢体畸形、唇腭裂、泌尿生生殖道畸形、外耳畸形、神经管畸形。各年龄组产妇的围产儿出生缺陷发生率差异无统计学意义(P>0.05)。结论加强孕前孕早期保健知识宣传教育,开展产前筛查、产前诊断和新生儿疾病筛查工作,是预防和减少出生缺陷的关键措施。
Objective To analyze the monitoring data of birth defects in Dongtai from 2007 to 2011, and to provide basis for further reducing the incidence of birth defects and exploring practical interventions. Methods According to the national birth defects monitoring program, we monitored the perinatal delivery in 29 monitoring hospitals in Dongtai from 2007 to 2011. Results Of the 34 498 perinatal children, 148 were born with birth defects and the incidence of birth defects was 4.29 ‰. There was no significant difference in birth defects rate at 5 years (P> 0.05). The first five birth defects were: limb deformity, cleft lip and palate, genitourinary tract deformities, external ear deformities, neural tube defects. There was no significant difference in the incidence of perinatal birth defects between maternal age groups (P> 0.05). Conclusion Strengthening early public health awareness education in preconception pregnancy, carrying out prenatal screening, prenatal diagnosis and neonatal disease screening are the key measures to prevent and reduce birth defects.