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目的探讨高血压合并高尿酸血症患者的血脂水平情况。方法选取2012年1月—2014年5月上海市徐汇区枫林街道社区卫生服务中心收治的高血压患者550例,进行血尿酸(UA)、血脂测定,根据UA水平分为高尿酸血症组190例和尿酸正常组360例,比较两组血脂情况。结果 550例患者平均(71.1±11.3)岁,男264例,平均年龄(70.5±12.0)岁;女286例,平均年龄(71.7±10.6)岁,男女患者年龄比较,差异无统计学意义(P>0.05)。男女患者血脂、UA水平比较,差异有统计学意义(P<0.05)。两组患者TG水平比较,差异有统计学意义(P<0.05)。入选高血压患者中34.55%有高尿酸血症,其中男89例,占男性患者33.71%,UA为(499.48±75.93)μmol/L,女性101例,占女性患者35.31%,UA为(435.22±71.42)μmol/L,男女高脂血症患者UA比较,差异无统计学意义(P>0.05)。40~49岁男女患者高尿酸血症患病率比较,差异有统计学意义(P<0.05)。结论高血压患者高尿酸血症患病率高,特别是合并高三酰甘油血症时,及早筛查并进行积极干预具有重要意义。
Objective To investigate the level of serum lipids in hypertensive patients with hyperuricemia. Methods From January 2012 to May 2014, 550 cases of hypertensive patients admitted to Fenglin Street Community Health Service Center, Xuhui District, Shanghai were enrolled in this study. Blood UA and blood lipids were measured. UA levels were divided into hyperuricemia group 190 cases and normal uric acid group 360 cases, comparing the two groups of blood lipids. Results A total of 550 patients (71.1 ± 11.3) years, 264 males, mean age (70.5 ± 12.0) years; 286 women, mean age (71.7 ± 10.6) years of age, male and female patients age comparison, the difference was not statistically significant > 0.05). Blood fat and UA levels in male and female patients were significantly different (P <0.05). TG levels of two groups of patients, the difference was statistically significant (P <0.05). 34.55% of hypertensive patients had hyperuricemia, including 89 males, accounting for 33.71% of male patients, UA of (499.48 ± 75.93) μmol / L, 101 females, accounting for 35.31% of female patients and UA of (435.22 ± 71.42) μmol / L. There was no significant difference in UA between male and female patients with hyperlipidemia (P> 0.05). The prevalence of hyperuricemia in 40-49 years old men and women was significantly different (P <0.05). Conclusions The prevalence of hyperuricemia in hypertensive patients is high, especially in patients with hypertriglyceridemia. It is of great importance to screen early and to actively intervene.