经胃镜诊断HP相关性十二指肠溃疡61例,每人每年平均至少2次以上的复发病史,随机分为两组:治疗组32例,对照组29例.两组性别、年龄、吸烟与否及病情均相当.治疗方法:两组均以4周为一疗程,治疗组Losec 20mg每天1次加用Amoxcillin 500mg每天4次,治疗1周后随后单用Losec 20mg每天1次,继续治疗3周.对照组单用Losec 20mg,每天1次共疗程4周.两组于治疗结束后4周复查胃镜及HP检查. 61 cases of HP-associated duodenal ulcer diagnosed by gastroscopy, with an average of at least 2 recurrences per patient per year, were randomly divided into two groups: 32 cases in the treatment group and 29 cases in the control group.The gender, age, smoking and No and the condition is quite.Methods: Both groups were treated with 4 weeks, treatment group Losec 20mg once daily with Amoxcillin 500mg 4 times a day, after 1 week of treatment with Losec 20mg once a day, continue treatment 3 Week.The control group was treated with Losec 20 mg once daily for 4 weeks.The gastroscopy and HP examination were performed in both groups 4 weeks after the end of treatment.