已知结核菌等抗酸菌感染在早期(2～3周)可诱导产生抑制性巨噬细胞,这虽为一过性的,但对于感染后期以抑制性T细胞为主导的免疫不应性的形成有重要作用。近年Convi(?)等由BCG活菌加热杀的麻风菌制成的疫苗已得到临床应用,且麻风菌的特异性抗原的编码基因已被克隆化,人们正在探索将这种基因导入BCG菌体内的最适方法。但EGC本身就是一种极强的诱导物.可引起上述抑制性巨噬细胞 It is known that tubercle bacillus and other acid-fast bacilli infections can induce the production of suppressive macrophages in the early stage (2-3 weeks). Although transient, it is known that suppressive T cells predominate during the later stage of infection The formation of an important role. In recent years, Convita (?) And other live BCG bacteria killed by heat-cured leprosy vaccine has been clinically applied, and leprosy specific antigen-encoding genes have been cloned, it is being explored into this gene into BCG bacteria The most suitable method. But EGC itself is a very strong inducer that can cause the above-mentioned inhibitory macrophages