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有研究表明，石棉和多环芳烃（ＰＡＨｓ）有协同致癌作用。其机制之一可能是石棉纤维使多环芳烃的排泄推迟，在体内停留时间延长，有利于与体内生物大分子作用［１］。另外，石棉还可能通过改变机体内依赖细胞色素Ｐ４５０的单氧化酶活性，影响多环芳烃的代谢，从而促进其...
Studies have shown that asbestos and polycyclic aromatic hydrocarbons (PAHs) have a synergistic carcinogenic effect. One of its mechanisms may be asbestos fibers to delay the excretion of polycyclic aromatic hydrocarbons, stay in the body longer, is conducive to the role of biological macromolecules in vivo [1]. In addition, asbestos may also affect the metabolism of polycyclic aromatic hydrocarbons by changing the activity of the body’s cytochrome P450-dependent monooxygenase ...