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目的研究探讨共用剃刀等危险因素与丙型肝炎传播的关系。方法对311名单纯抗-HCV检测为阳性的献血者及622名阴性献血者进行病例对照研究,应用多因素条件Logistic回归模型分析与感染因素,研究发现使用共用剃刀、牙科治疗史、住院史、乙肝家族史、输血史等可以增加HCV感染的危险性,其危险度(OR)分别是:2.080、2.380、2.176、2.438和7.177,人群归因危险度分别是:15.30%、25.66%、10.60%、3.03%和1.84%,5项危险因素总的人群归因危险度为46.08%结论共用剃刀以及可能导致血液接触的器具是丙型肝炎传播的危险因素。
Objective To study the relationship between risk factors such as sharing razor and hepatitis C transmission. Methods A total of 311 blood donors with positive anti-HCV tests and 622 negative blood donors were enrolled in this study. Multivariate Logistic regression analysis and infection factors were used to investigate the effects of common razors, dental treatment history, hospitalization history, Family history of hepatitis B, history of blood transfusion and so on can increase the risk of HCV infection, the risk (OR) were 2.080,2.380,2.176,2.438 and 7.177, the risk attributable to the population were: 15.30%, 25.66%, 10.60% , 3.03% and 1.84%, respectively. The total risk of at-risk of the five risk factors was 46.08% Conclusion The common razor and the appliance that may cause blood contact are the risk factors of hepatitis C transmission.