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本文观察了急性脑梗塞（ＡＣＩ）病人白细胞变形能力（ＬＤ）的变化，同时检测了血浆总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、纤维蛋白原（Ｆｉｇ）、脂质过氧化物代谢产物丙二醛（ＭＤＡ）和血浆镁离子的浓度变化。结果显示，ＡＣＩ病人ＬＤ较对照组明显降低，差异有显著性意义（Ｐ＜０．００１），且ＬＤ随着血浆ＴＣ、ＴＧ、Ｆｉｇ、ＭＤＡ浓度增高和血镁浓度降低而进一步降低。本结果提示，在预防和治疗ＡＣＩ过程中，提高ＬＤ，改善微循环，对增加缺血脑组织的血液灌流，缩小梗塞面积和改善预后具有重要的临床意义。
In this paper, the changes of leukocyte deformability (LD) in patients with acute cerebral infarction (ACI) were observed. The levels of total cholesterol (TC), triglyceride (TG), fibrinogen (Fig), lipid peroxide metabolites Malondialdehyde (MDA) and plasma magnesium concentration changes. The results showed that the LDL of ACI patients was significantly lower than that of the control group (P <0.001), and LD decreased further with the increase of plasma TC, TG, Fig, MDA concentration and serum magnesium concentration. The results suggest that in the prevention and treatment of ACI process, improve LD, improve microcirculation, to increase blood flow in ischemic brain tissue, reduce infarct size and improve prognosis has important clinical significance.