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目的:分析结核病患者的耐药特点为临床治疗提供依据。方法:回顾分析我院2011~2013年分离培养出的结核分枝杆菌936例,采用BD680自动鉴定仪进行培养鉴定和比例法进行药敏试验。结果:结核病患者耐药性较高的主要有异烟肼、利福平和链霉素,复治患者耐药性明显比初治高。结论:结核病耐药性严重,复治患者的耐药性有显著差异,临床上应针对不同个体建立不同治疗方案,加强耐药监测,防止恶化。
Objective: To analyze the drug resistance of patients with tuberculosis to provide the basis for clinical treatment. Methods: A retrospective analysis of our hospital from 2011 to 2013, 936 cases of Mycobacterium tuberculosis isolated and cultured by BD680 automatic identification instrument for the identification of culture and susceptibility testing. Results: The patients with high resistance to tuberculosis were mainly isoniazid, rifampicin and streptomycin, and the patients with retreatment were significantly more resistant than those without initial treatment. Conclusion: The drug resistance of tuberculosis is serious, there is a significant difference in the drug resistance of retreatment patients. Clinically, different treatment programs should be established for different individuals so as to strengthen the drug resistance monitoring and prevent the deterioration.