论文部分内容阅读
从药用植物滨海前胡Peucedanumjaponicum Thunb根的乙醚提取物中分离得到香豆素(1),它是该植物中的一个主要活性成分,是一个乙酰当归克拉草内酯和乙酰惕各酰克拉草内酯的混合物。同时还从中药白花前棚Peucedanum praeruptorum Kunn)根的甲醇提取物中分离得到数种香豆素,这些香豆索具有抗胆碱能,抗组胺和钙离子阻断作用,其中以白花前胡素A(praeruptorin A=Pd-la,2)的活性为最强。为了研究上述两种活性成分的化学结构,合成了八种香豆素
The coumarin (1), which is a major active ingredient in this plant, is obtained from the ether extract of the medicinal plant Pegandanum japonicum Thunb root, which is an acetylallerocaldactone and acetylacetonate. A mixture of lactones. At the same time, several coumarins were isolated from the methanol extract of the root of Chinese herb Peeddanum praeruptorum Kunn. These coumadins have anticholinergic, antihistamine and calcium-blocking effects, among which Baihua Qianhu The activity of praeruptorin A=Pd-la,2 is the strongest. In order to study the chemical structure of the above two active ingredients, eight coumarins were synthesized.