论文部分内容阅读
目的低血糖反应常见于1型糖尿病及长期应用胰岛素的2型糖尿病患者。低血糖感知受损(Impaired Awareness of Hypoglycemia,IAH)在糖尿病患者当中亦常见,并且是一个重要的危险因素,IAH可以导致严重低血糖(Severe Hypoglycemia,SH),对低血糖感知受损的综合评估可以减少糖尿病患者因低血糖造成的不良事件及影响。如何准确识别IAH的发生,对预防和减少SH的发生具有重要的意义。方法通过比较目前国际上较为流行的几种评估低血糖感知受损的方法—Clarke、Gold、Pederson-Bjergaard、低血糖调查问卷方法,来综合评估低血糖感知受损。结果通过上述四种方法可以识别IAH的发生,联合使用两种或两种以上的方法可以提高IAH的识别率,从而较大地减少低血糖对糖尿病患者造成的危害。结论上述四种评估方法有各自的局限性。Clarke和Gold方法依然是当前最常用的评估IAH的方法。只有识别IAH,才能预防和减少SH的发生。此外,还特别需要注意的是,要在临床实践中积极识别那些合并IAH的2型糖尿病患者。
Purpose Low blood glucose response is common in type 1 diabetes and long-term insulin-requiring type 2 diabetes. Impaired Awareness of Hypoglycemia (IAH) is also common in diabetic patients and is an important risk factor. IAH can cause severe hypoglycemia (SH), a comprehensive assessment of hypoglycemic perception impairment Can reduce the adverse events and the effects caused by hypoglycemia in diabetic patients. How to accurately identify the occurrence of IAH, to prevent and reduce the occurrence of SH is of great significance. Methods The hypoglycemic perceptual impairment was evaluated by comparing the most commonly used methods of assessing hypoglycaemia, Clarke, Gold, Pederson-Bjergaard and hypoglycaemia questionnaire. Results The above four methods can identify the occurrence of IAH. The combined use of two or more methods can improve the recognition rate of IAH, thus greatly reducing the risk of hypoglycemia in patients with diabetes. Conclusion The four assessment methods have their own limitations. The Clarke and Gold methods remain the most commonly used method for assessing IAH today. Only identify IAH, can prevent and reduce the occurrence of SH. In addition, it is also important to note that in clinical practice, patients with type 2 diabetes mellitus who have IAH should be positively identified.