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目的研究131I治疗甲状腺功能亢进伴2型糖尿病患者的临床效果。方法对入院治疗的90例甲状腺功能亢进伴2型糖尿病患者进行了研究,随机分为二组,对照组患者在基础治疗之上,给予甲巯咪唑,观察组患者采用131 I进行治疗,比较二组患者治疗前后甲状腺激素水平及血糖水平,二组患者的临床症状改善程度比较,二组患者甲状腺大小改变情况以及临床总有效率。结果观察组患者甲状腺激素水平以及血糖指标均明显低于对照组,差异有统计学意义(P<0.05);观察组患者多汗、怕热、多食等临床症状的发生率明显低于对照组,差异有统计学意义(P<0.05);观察组患者的甲状腺明显变小,好于对照组,二组比较差异有统计学意义(P<0.05);观察组临床总有效率为93.3%,对照组临床总有效率为80.0%,二组比较差异有统计学意义(P<0.05)。结论 131I治疗甲状腺功能亢进伴2型糖尿病患者临床效果显著,改善患者的激素水平和血糖水平更明显,观察组患者临床症状的改善程度明显好于对照组,并且观察组患者的甲状腺更小,临床总有效率更高,值得临床推广应用。
Objective To study the clinical effect of 131I in the treatment of patients with hyperthyroidism and type 2 diabetes mellitus. Methods 90 cases of hyperthyroidism with type 2 diabetes mellitus admitted to hospital were studied and randomly divided into two groups. Patients in the control group were treated with methimazole on the basis of the basic treatment, and 131 I in the observation group was used for treatment. Thyroid hormone levels and blood glucose levels before and after treatment in the group of patients, two groups of patients to compare the degree of improvement of clinical symptoms, thyroid size changes in two groups of patients and the total effective rate of the clinic. Results The levels of thyroid hormone and blood glucose in the observation group were significantly lower than those in the control group (P <0.05). The incidences of clinical symptoms such as hyperhidrosis, febrile and overdose in the observation group were significantly lower than those in the control group , The difference was statistically significant (P <0.05); the observation group patients thyroid was significantly smaller, better than the control group, the difference between the two groups was statistically significant (P <0.05); observation group, the total effective rate was 93.3% The total effective rate of the control group was 80.0%, the difference between the two groups was statistically significant (P <0.05). Conclusion 131I treatment of hyperthyroidism with type 2 diabetes patients with significant clinical effect, to improve the patient’s hormone levels and blood glucose levels were more obvious, the observation group patients improved significantly better clinical symptoms, and the observation group patients with smaller thyroid gland, clinical The total efficiency is higher, it is worth clinical application.