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目的:调查、分析住院精神疾病患者的药物治疗情况,为临床合理用药提供参考依据。方法:采用一日法对福建省精神卫生中心553例住院精神疾病患者的精神药物处方应用情况进行调查。结果:本院住院患者大部分为20～49岁的青壮年,以精神分裂症为主,抗精神病药物合并其他药物现象比较普遍,但以单用一种抗精神病药物的药物治疗方案为主,联用二种抗精神病药物也很常见,抗精神病药物使用排在前五位的为:奥氮平、利培酮、氯氮平、氯丙嗪、奋乃静,新一代抗精神病药物已居临床用药主导地位,抗精神药联用镇静催眠药和心境稳定剂有利于精神病治疗。结论:精神疾病的药物治疗方案多样化是一种趋势,在提高疗效的同时,应当注意如何避免药物相互作用,减少药品不良反应,实现个体化给药。
Objective: To investigate and analyze the medical treatment of inpatients with mental illness and to provide a reference for rational clinical use. Methods: One-day method was used to investigate the psychotropic prescriptions of 553 inpatients with mental illness in Fujian Mental Health Center. Results: The majority of hospitalized patients in our hospital were young adults aged 20 to 49 years, mainly schizophrenia. Antipsychotics combined with other drugs were more common. However, taking only one kind of antipsychotic drug treatment plan, Combination of two antipsychotic drugs is also common, top five antipsychotic drugs used are: olanzapine, risperidone, clozapine, chlorpromazine, perphenazine, a new generation of antipsychotics have been living Dominant clinical medication, antipsychotic sedative and hypnotic drugs and mood stabilizers help psychiatric treatment. Conclusion: The diversification of drug treatment programs for mental illness is a trend. While improving the curative effect, we should pay attention to how to avoid drug interactions, reduce drug adverse reactions and achieve individualized administration.