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核酸疫苗又称ＤＮＡ疫苗 ,是指将含有编码某种目的抗原蛋白基因序列的真核细胞表达质粒作为疫苗 ,直接接种机体 ,在体内合成抗原蛋白 ,诱导宿主产生对该抗原蛋白的免疫应答 ,达到免疫的目的。乙肝ＤＮＡ疫苗的抗原基因片段 ,主要是编码表面抗原的Ｓ区 ,也可包括ｐｒｅＳ1 、ｐ?
Nucleic acid vaccine, also known as DNA vaccine, refers to the eukaryotic expression plasmid containing a gene sequence encoding a certain antigen of interest as a vaccine, which is directly inoculated into the body to synthesize antigenic protein in vivo to induce the host to produce an immune response to the antigenic protein Immune to the purpose. Hepatitis B DNA vaccine antigen gene fragments, mainly encoding the surface antigen S region, may also include preS1, p?