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目的比较原发性与继发性反复自然流产妇女的流行病学特点。方法选取2014年1月-2015年6月在该院妇产科门诊就诊的139例反复自然流产患者为研究对象,根据既往是否有过正常妊娠分娩史分为对照组(继发性反复自然流产)与研究组(原发性反复自然流产),分别为36例、103例。分析两组患者年龄、体重、身高、体重指数(BMI)、停育次数、孕产史、病因构成及妊娠结局。结果研究组患者年龄、既往妊娠次数分别为(27.84±4.93)岁、(2.68±1.21)次,明显低于对照组[(30.85±3.04)岁、(3.85±1.19)次],差异有统计学意义(P<0.05);研究组封闭抗体阴性、染色体异常患者所占比例高于对照组,而其他病因患者所占比例低于对照组(P<0.05);两组身高、体重、BMI、结婚年龄、停育次数、抗磷脂抗体综合征患者所占比例、妊娠与再次流产、成功妊娠患者受孕方式、分娩方式相比,差异均无统计学意义(P>0.05)。结论在一般情况方面,原发性反复自然流产患者年龄、既往妊娠次数低于继发性反复自然流产患者,其余各项无明显差异;在病因方面,两者病因构成不同;在妊娠结局方面,两者未见明显差异。
Objective To compare the epidemiological characteristics of women with primary and secondary recurrent spontaneous abortion. Methods From January 2014 to June 2015, 139 cases of recurrent spontaneous abortion in obstetrics and gynecology outpatient department of the hospital were selected as the research object. According to the past history of normal pregnancy delivery, the patients were divided into control group (secondary recurrent spontaneous abortion ) And study group (primary recurrent spontaneous abortion), respectively, 36 cases, 103 cases. The age, weight, height, body mass index (BMI), number of cessation, history of pregnancy, etiology and pregnancy outcome were analyzed. Results The age and the number of previous pregnancy in the study group were (27.84 ± 4.93) and (2.68 ± 1.21) times, respectively, which were significantly lower than those in the control group [(30.85 ± 3.04) and (3.85 ± 1.19), respectively) (P <0.05). In the study group, the number of negative antibody and chromosomal abnormality was higher in the study group than in the control group, while the proportions of other causes were lower than those in the control group (P <0.05). The height, weight, BMI, There was no significant difference in the age, number of outpatients, the proportion of patients with antiphospholipid antibody syndrome, pregnancy and recurrent spontaneous abortion, pregnancy mode and mode of delivery in successful pregnancy (P> 0.05). Conclusion In the general situation, the age of patients with primary recurrent spontaneous abortion, the number of previous pregnancies is lower than that of patients with secondary recurrent spontaneous abortion, the other no significant difference; in the cause, the two causes are different; in the outcome of pregnancy, No significant difference between the two.