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目的 观察舒氨西林治疗恶性血液病合并感染的疗效。方法 轻中度感染 ,舒氨西林 3 0～ 4 5 g/d ,重度感染 ,4 5～ 6 0 g/d ,分两次静脉点滴 ,疗程 7～ 10d。结果 舒氨西林治疗恶性血液病并感染总有效率为 83 3% ,其中轻中度感染与重度感染有效率分别为 88 9%及 6 6 7% ,差异有显著性 (χ2 =11 2 0 3,P <0 0 0 1) ,不同病种、不同部位感染有效率差异无统计学意义 (χ2 =0 82 0 3及 1 6 483,P >0 0 5 )。结论 舒氨西林是一种安全有效的抗生素 ,可以作为恶性血液病并轻中度感染的一线抗菌药物。
Objective To observe the efficacy of sumacillin in the treatment of hematological malignancies combined with infection. Methods mild to moderate infections, 3 to 4 5 g/d with desamipinil, severe infection, 4 to 60 g/d, two intravenous drip, course of treatment 7 to 10 days. Results The total effective rate of sumacilillin in treatment of hematological malignancies and infection was 83 3%. The effective rates of mild to moderate infection and severe infection were 88 9% and 66.7% respectively. The difference was significant (χ 2 =11 2 0 3 ,P < 0 0 0 1), There was no significant difference in the effective rate of infection between different diseases and different sites (χ2 = 0 82 0 3 and 1 6 483, P > 0 05). Conclusions Shuxicillin is a safe and effective antibiotic and can be used as a first-line antibacterial agent for hematological malignancies with mild to moderate infections.