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对于患有终末期肾病的育龄期女性,肾移植是恢复其生育功能的有效治疗手段之一。但由于免疫抑制剂的使用等特殊情况,有一系列妇产科相关问题亟需解答,如妊娠时机的把握、避孕方式的选择、妊娠对移植肾的影响、免疫抑制剂对胎儿的影响及剂量调整问题、辅助生育技术的应用问题、产科并发症的发生及新生儿结局的影响等。随着越来越多的肾移植后妊娠及良好产科结局报道,肾移植后妊娠需求不断增加,前景较为明朗。现对肾移植后妊娠相关问题作一综述。
For women of childbearing age who suffer from end-stage renal disease, kidney transplantation is one of the most effective treatments to restore their fertility. However, due to the special circumstances such as the use of immunosuppressive agents, there are a series of obstetrics and gynecology-related issues in urgent need of solution, such as grasping the timing of pregnancy, the choice of contraceptive methods, the impact of pregnancy on the renal graft, immunosuppressive agents on the fetus and dose adjustment Problems, the application of assisted reproductive technology, the occurrence of obstetric complications and the impact of neonatal outcomes. As more and more pregnancies after kidney transplantation and good obstetrical outcomes are reported, there is a growing demand for pregnancy after kidney transplantation, with a clearer outlook. Now the pregnancy related issues after renal transplantation are reviewed.