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目的:探讨肝动脉内植入药盒导管系统(PCS)的最佳径路。材料与方法:216例中晚期肝癌,118例采取经皮左锁骨下动脉(LSA)径路肝动脉内植入PCS,另外98例采取经皮股动脉(FA)径路植入PCS。统计两种植入方法的成功率、并发症。结果:LSA组与FA组植入成功率分别为91.5%和88.7%(P>0.05)。LSA组植入失败的10例为动脉穿刺失败8例,靶动脉迂曲留置管无法置入2例;FA组失败11例均为留置管无法植入靶动脉内,其中腹腔动脉干过长5例,肝右动脉(靶动脉)起自肠系膜上动脉3例,靶血管迂曲3例。LSA组气胸4例,留置管移位12例,而FA组留置管移位11例。移位率分别为10.2%和11.2%。结论:常规采取FA径路肝动脉内植入PCS安全可行。对腹腔动脉、肝动脉解剖变异者采取LSA法能够提高植入术成功率,降低留置管移位率
Objective: To explore the optimal pathway for the implantation of a PCS catheter in the hepatic artery. Materials and Methods: 216 patients with advanced liver cancer were enrolled in this study. 118 patients were percutaneously implanted into the hepatic artery of the left subclavian artery (LSA), and another 98 patients were implanted with PCS through the transfemoral artery (FA). Statistics the success rate and complications of the two implantation methods. Results: The implantation success rate of LSA group and FA group was 91.5% and 88.7%, respectively (P>0.05). In the LSA group, failure of implantation failed in 8 cases (8 cases failed in arterial puncture, 2 cases could not be placed in the target artery indwelling catheter), and 11 cases in the FA group failed to be implanted into the target artery by indwelling catheter. The right hepatic artery (target artery) originated from the superior mesenteric artery in 3 cases and the target vessels in 3 cases. There were 4 cases of pneumothorax in LSA group and 12 cases of indwelling tube displacement, while 11 cases of indwelling tube displacement in FA group. The shift rates were 10.2% and 11.2%, respectively. Conclusion: It is safe and feasible to implant PCS into the hepatic artery via FA route. The use of LSA for celiac artery and hepatic artery anatomy and variability can improve the success rate of implantation and reduce the rate of indwelling tube displacement.