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目的对早产儿宫外生长发育迟缓(EUGR)的发生情况及相关危险因素进行了临床研究,为临床中减少早产儿EUGR提供理论指导。方法对南山医院2009年1月-2011年12月新生儿科住院的早产儿,共357例,对发生EUGR的危险因素进行分析。结果 <32周组、32～35周组和>35周组按照出生体重和出生头围评价,差异无统计学意义(P>0.05);<1500 g组、1500 g～组和≥2500 g组按照出生体重和出生头围评价,差异均有统计学意义(P<0.05)。危险因素纳入多因素Logistic回归分析,得出体重EUGR的危险因素:出生胎龄、出生体重。头围EUGR的危险因素:出生头围、是否头围IUGR和静脉氨基酸最大量。结论指导孕妇加强营养支持,避免影响早产的各种因素,同时,早期给予出生后早产儿充足的能量及各种营养素,均有利于患儿未来的体格及智力发育。
Objective To study the incidence of ectopic growth retardation (EUGR) in preterm infants and related risk factors, and provide theoretical guidance for reducing EUGR in premature infants. Methods A total of 357 preterm infants hospitalized in neonatology department of Nanshan Hospital from January 2009 to December 2011 were retrospectively analyzed. Risk factors of EUGR were analyzed. Results There was no significant difference between the groups <32 weeks, 32-35 weeks and> 35 weeks according to birth weight and birth head circumference (P> 0.05); <1500 g group, 1500 g-group and ≥2500 g group According to birth weight and head circumference evaluation, the differences were statistically significant (P <0.05). Risk factors into multivariate Logistic regression analysis, the risk factors of weight EUGR: birth gestational age, birth weight. Risk factors for head circumference EUGR: Born head circumference, whether head circumference IUGR and maximum amount of intravenous amino acids. Conclusions Guidance for pregnant women to strengthen nutritional support, to avoid affecting the various factors of preterm birth, while giving prenatal early enough energy and nutrients, are conducive to the children’s physical and mental development in the future.