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目的探讨妊娠期妇女生殖道假丝酵母菌病对妊娠不良结局的影响。方法回顾性分析2011年1月-2014年2月在我院住院孕产妇共2500例,进行阴道分泌物细菌培养,对白色念珠菌培养阳性组与正常对照组的妊娠结局进行分析,以探讨妊娠合并生殖道假丝酵母菌病与围产期并发症的关系。结果在2500例围产期妇女中,无致病菌组(对照组)为1300例,假丝酵母菌培养阳性组(感染组)为350例,总患病率为14%,其中有症状组200例(57.14%),无症状组为150例(42.86%)。有症状感染组、无症状感染组、对照组的胎膜早破的发生率分别为22.5%、9.33%、8.15%,早产率分别为9.5%、4%、3%,绒毛膜羊膜炎率分别为23%、8.67%、7.38%,产褥感染率分别为7.5%、4%、3.54%,新生儿黄疸的发生率分别为21%、10.67%、11.54%,新生儿窒息率分别为2%、2.67%、2.31%,低体重儿的发生率分别为1.5%、1.33%、1.92%。有症状的妊娠期妇女生殖道假丝酵母菌病与无症状组及对照组相比较,胎膜早破、早产、绒毛膜羊膜炎、产褥感染、新生儿黄疸的发生率均有显著升高,新生儿窒息率及低体重儿的发生率无显著性差异。结论孕期对有症状的生殖道假丝酵母菌病的治疗是有重要意义的。
Objective To investigate the effect of genital tract Candida during pregnancy on the adverse pregnancy outcome in pregnant women. Methods Retrospective analysis from January 2011 to February 2014 in our hospital a total of 2500 pregnant women in the hospital for vaginal secretion bacterial culture, positive control group of Candida albicans culture positive control group and the outcome of pregnancy to explore the pregnancy Relationship between genital tract Candida and perinatal complications. Results Of 2500 women of perinatal age, there were 1300 cases of non-pathogenic bacteria (control group), 350 cases of positive Candida culture group (infection group), the total prevalence rate was 14%, of which symptoms group 200 cases (57.14%), asymptomatic group was 150 cases (42.86%). The incidence of premature rupture of membranes in patients with symptomatic infection, asymptomatic infection and control group were 22.5%, 9.33%, 8.15%, preterm birth rates were 9.5%, 4%, 3%, chorioamnionitis rates The rates of puerperal infection were 7.5%, 4% and 3.54% respectively. The incidences of neonatal jaundice were 21%, 10.67% and 11.54% respectively. The rates of neonatal asphyxia were 2% , 2.67%, 2.31%, the incidence of low birth weight children were 1.5%, 1.33%, 1.92%. Compared with asymptomatic group and control group, the prevalence of premature rupture of membranes, premature labor, chorioamnionitis, puerperal infection and neonatal jaundice in symptomatic women during pregnancy were significantly higher than those in asymptomatic and control groups , Neonatal asphyxia and low birth weight infants no significant difference. Conclusion The treatment of symptomatic genital tract Candida is of great significance during pregnancy.