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目的:观察自发性脑出血(SICH)患者甘露醇治疗前后脑水肿的动态演变。方法:选择30例SICH患者在甘露醇治疗前、后不同时点运用无创脑水肿动态监护仪动态检测扰动系数。结果:治疗后30 min、1 h、3 h脑出血侧和对侧分别与治疗前比较,有显著性差异(P<0.01);在治疗5 d脑出血侧与对侧相比,有显著性差异(P<0.01),第7天无差异;SICH患者出血侧在治疗后第7天与治疗前比较有显著性差异(P<0.01)。结论:甘露醇治疗3 h后SICH患者全脑脑水肿减轻,脑出血侧脑水肿在用药后5 d内一直重于对侧,第7天出血侧脑水肿减轻。
Objective: To observe the dynamic changes of brain edema in patients with spontaneous cerebral hemorrhage (SICH) before and after mannitol treatment. Methods: Thirty patients with SICH were selected to detect the disturbance coefficient dynamically at different time points before and after mannitol treatment with a non-invasive brain edema dynamic monitor. Results: There were significant differences in the cerebral hemorrhage side and the contralateral side at 30 min, 1 h and 3 h after treatment, respectively (P <0.01). Compared with the contralateral side at 5 d after treatment, there was significant difference (P <0.01). There was no difference on the 7th day. The hemorrhage side of SICH patients was significantly different from that before treatment on the 7th day after treatment (P <0.01). Conclusion: Cerebral edema in patients with SICH is relieved after 3 hours of mannitol treatment. Cerebral hemorrhage in patients with intracerebral hemorrhage is heavier on the opposite side within 5 days after treatment and is reduced on the 7th day.