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基质细胞衍生因子1(Stromal cell-derived factor-1,SDF-1)是不同类型细胞分泌的低分子量(8～10kD)细胞因子,它对白细胞亚类如中性粒细胞、单核细胞、淋巴细胞具有趋化和预激活作用。而趋化因子受体CXCR4是一类含有7个跨膜区的G蛋白耦联受体,它作为目前已知的SDF-1惟一受体广泛
Stromal cell-derived factor-1 (SDF-1) is a low-molecular-weight (8-10 kD) cytokine secreted by different cell types. It inhibits leukocyte subclasses such as neutrophils, monocytes, Cells have chemotaxis and preactivation. The chemokine receptor CXCR4 is a class of G-protein-coupled receptors with seven transmembrane domains that serve as the only known receptor for SDF-1