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原发性高血压患者中尿微量白蛋白排泄率(UAE)增高已被肯定,且与病程及血压升高程度有关。亚临床数量白蛋白尿的出现是一种继发于高血压肾内异常血液动力学的结果。UAE的增高对原发性高血压患者可作血管损伤的早期预报。它是原发性高血压心血管合并症的发病率及死亡率的一个独立的危险因素;中比眼底,心超更敏感的指标。能否作预测高血压合并肾脏病变发生的指标,尚需长期研究。此外,用UAE为指征进行降压药长期及短期的研究发现转换酶抑制剂能减少蛋白尿,改善肾功能.对肾脏具有保护作用。
Urinary microalbuminuria (UAE) increased in patients with essential hypertension has been affirmed, and with the extent of the disease and the rise in blood pressure. The appearance of subclinical albuminuria is a consequence of abnormal renal hemodynamics secondary to hypertension. Increased UAE can be used for early prediction of vascular injury in patients with essential hypertension. It is an independent risk factor for morbidity and mortality in patients with essential hypertension with cardiovascular comorbidities; more sensitive to ocular fundus than to fundus. Can predict the occurrence of hypertension with renal disease indicators, the need for long-term study. In addition, long-term and short-term studies using antihypertensive drugs as indications for UAE found that converting enzyme inhibitors reduce proteinuria and improve renal function. Has a protective effect on the kidneys.