论文部分内容阅读
在毛主席无产阶级革命卫生路线指引下,我院附属医院慢性气管炎防治组从1971年开始选用中草药茛菪子制剂治疗了慢性气管炎近2,000例,无论针剂、片剂和汤剂都取得了良好的疗效。经过实验证明,茛菪子的有效成分主要是东茛菪碱和阿托品等生物碱,具有抗胆碱作用,并根据临床和实验室的探索工作,初步发现这类抗胆碱药对慢性气管炎的疗效可能与消除迷走神经的异常兴奋,从而调整了植物神经的机能有关。鉴于慢性气管炎综合病因中过敏与免疫因素亦为重要的一环,因此既要探讨全身免疫因素,又要弄清局部免疫因素及其相互联系,以便给慢性气管炎提供疗效指标和防治依据。过去曾有人研究过植物神经药对免疫反应的影响,近年来又有人证明植物神经能影响肥大细胞的脱颗粒过程。这就有可能使茛菪子治疗同慢性气管炎的免疫学研究联系起来。为此本文试从茛菪子治疗与慢性气管炎病人局部抗体IgA的变化进行初步探讨。现将结果报告如下。
Under Chairman Mao’s revolutionary proletarian revolutionary line of hygiene, the Chronic Bronchitis Prevention and Control Unit of the Affiliated Hospital of our hospital has been treating nearly 2,000 chronic bronchitis patients since 1971. Both injections, tablets and decoctions have been made Good effect. After experiments show that the active ingredient Scopolamine is mainly scopolamine and atropine and other alkaloids, with anticholinergic effects, and based on clinical and laboratory exploration, and initially found that such anticholinergic agents may have the effect of chronic bronchitis And eliminate the abnormal excitement of the vagus nerve, thus adjusting the function of autonomic. In view of the integrated cause of chronic bronchitis allergy and immune factors is also an important part, it is necessary to explore systemic immune factors, but also to understand the local immune factors and their interlinked, in order to provide therapeutic indicators and prevention of chronic bronchitis basis. In the past, the effects of autonomic drugs on immune responses have been studied. In recent years, it has also been shown that autonomic nerves can affect the degranulation of mast cells. This makes it possible to link cucurbitacin to immunological studies of chronic bronchitis. For this reason, this article tries to discuss the change of IgA in the local antibody in patients with chronic bronchitis treated with scopolamine. The results reported below.