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目的:应用磁源性影像技术探讨在简单视-运动任务活动时的脑增龄性变化神经机制。方法:本文应用磁源性影像技术对13例20—85岁右利手健康男性进行简单视-运动任务活动时脑磁信号时间和空间的表现进行研究。结果:青年组和老年组受试者双手运动潜伏期基本一致,左手平均55ms,右手59ms,差异无显著性意义;脑运动皮层定位显示为双侧手指运动区。高龄老年组运动潜伏期延长,非利手侧较利手侧延长更加明显,平均90—127ms;利手侧半球空间定位可见,而非利手侧半球未显示空间定位。结论:成年人随增龄所发生的运动功能减退主要发生在75岁以后高龄老年人;老年性脑改变导致脑功能普遍减退可能是成年人随增龄所发生的运动功能减退的神经机制之一;成年人随增龄所发生的运动功能减退以神经传导速度减慢和运动协调性差为特征;长期反复运动活动有利于延缓脑运动控制机能的减退速度。
Objective: To explore the neural mechanism of brain aging in simple visual-motor task by using magnetic-source imaging. Methods: Magnetic resonance imaging was used to study the temporal and spatial characteristics of brain magnetic signals in 13 simple right-handed task males aged 20-85 years old with magnetic source imaging. Results: The incubation period of both hands was basically the same in both young and old subjects. The left hand averaged 55 ms and the right hand 59 ms. There was no significant difference between the two groups. The cerebral cortical location showed bilateral finger movement area. Elderly elderly patients with motor latency increased, non-profit side more than the hand side of the extension is more obvious, with an average of 90-127ms; Lee hand hemisphere spatial positioning can be seen, rather than the hemiplegia hemisphere did not show spatial positioning. CONCLUSION: The decline of motor function in adults with age mainly occurs in elderly people after 75 years of age. The general decline of brain function caused by senile brain changes may be one of the neural mechanisms of motor function decline with age in adults The decline of motor function in adults with aging was characterized by slowing of nerve conduction velocity and poor motor coordination. Long-term repeated exercise was helpful to slow the decline of brain function.