肺动脉高压(PAH)是指静息时平均肺动脉压25mmHg,或运动时平均肺动脉压30mmHg。长期肺动脉高压可导致右心室后负荷增加,引起右心室肥厚和扩张,最后发展为慢性肺源性心脏病。因而肺动脉高压的严重程度直接影响肺心病患者的病程、生活质量和预后。近年来,关于肺动脉高压的治疗研 Pulmonary arterial hypertension (PAH) refers to a mean pulmonary artery pressure of 25 mm Hg at rest or an average pulmonary artery pressure of 30 mm Hg during exercise. Long-term pulmonary hypertension can lead to increased right ventricular afterload, causing right ventricular hypertrophy and dilatation, and eventually develops chronic pulmonary heart disease. Therefore, the severity of pulmonary hypertension directly affects the course, quality of life, and prognosis of patients with pulmonary heart disease. In recent years, research on the treatment of pulmonary hypertension