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目的研究丙泊酚与芬太尼和瑞芬太尼伍用在人工流产术中的效果。方法对100例健康早孕的人工流产患者随机分为两组,每组50例。A组静注丙泊酚2mg/kg,芬太尼1.0μg/kg。B组静注丙泊酚2mg/kg和瑞芬太尼1.0μg/kg。分别记录术中BP,HR,RR,SpO2,观察各组镇痛效果(按优,良,差三个等级进行效果评定),用药量,苏醒时间,定向力,并发症等。结果两组比较差异有显著性(P<0.050)。苏醒时间B组优于A组;术中镇痛效果依次为B组优于A组;呼吸抑制程度依次为A组大于B组。结论两组均可用于人工流产术,但以丙泊酚加瑞芬太尼效果为最好,用药量少,苏醒快,术后腹痛发生率较明显。
Objective To study the effects of propofol with fentanyl and remifentanil in artificial abortion. Methods 100 cases of early pregnancy induced abortion were randomly divided into two groups of 50 cases. Group A received intravenous propofol 2 mg / kg and fentanyl 1.0 μg / kg. Group B received intravenous propofol 2 mg / kg and remifentanil 1.0 μg / kg. The intraoperative BP, HR, RR and SpO2 were recorded. The analgesic effect (according to excellent, good and bad grades) was evaluated. The dosage, recovery time, orientation and complications were observed. Results There was significant difference between the two groups (P <0.050). The awakening time was better in group B than in group A; the analgesic effect in group B was superior to that in group A; the degree of respiration was higher in group A than in group B. Conclusion Both groups can be used for artificial abortion, but propofol plus remifentanil is the best, less dosage, faster recovery and more postoperative abdominal pain.