本文研究了绿原酸(5-CQA)及其同分异构体隐绿原酸(4-CQA)和新绿原酸(3-CQA)在中性和碱性p H条件下的降解规律。结果表明,3-、4-、5-CQA在酸性p H条件下较为稳定,在中性和碱性p H条件下不稳定,且随碱性的增强,降解越强烈,转化成的CQA总量越低,但并不生成咖啡酸。同时,3-CQA和5-CQA在水解时更趋向于转化为4-CQA,而4-CQA水解时更趋向于转化为3-CQA,而非5-CQA。通过比较中性和碱性p H条件下3-、4-、5-CQA的降解动力学参数发现,反应速率常数k值的大小顺序为4-CQA>3-CQA>5-CQA,降解半衰期t_(1/2)值的大小顺序为4-CQA<3-CQA<5-CQA,说明在中性和碱性p H条件下三者的稳定性顺序为4-CQA<3-CQA<5-CQA。 In this paper, the degradation of chlorogenic acid (5-CQA) and its isomers, chlorogenic acid (4-CQA) and neogenic chlorogenic acid (3-CQA) under neutral and alkaline pH conditions were studied. The results showed that 3-, 4- and 5-CQA were stable under acidic pH conditions and unstable under neutral and basic pH conditions. With the increase of alkalinity, the degradation of 3-, 4- and 5-CQA was stronger and the conversion of CQA The lower the amount, but does not produce caffeic acid. In the meantime, 3-CQA and 5-CQA tend to be converted to 4-CQA upon hydrolysis, whereas 4-CQA tend to be converted to 3-CQA instead of 5-CQA upon hydrolysis. By comparing the degradation kinetic parameters of 3-, 4-, and 5-CQA under neutral and basic pH conditions, it was found that the order of k value of reaction rate constant was 4-CQA> 3-CQA> 5- The order of the value of t_ (1/2) is 4-CQA <3-CQA <5-CQA, indicating that the stability order of the three under neutral and alkaline pH conditions is 4-CQA <3-CQA <5 -CQA.