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Tako-Tsubo心肌病又称为应激性心肌病、伤心综合征、左室心尖球囊综合征、短暂左室心尖球形改变等。最早由日本学者报道,其临床表现与急性心肌梗死极为相似,包括胸痛、心电图ST-T改变、左心室功能障碍,但其与急性心肌梗死的最大区别是,其左心室功能障碍是可逆性的,而且冠状动脉造影结果多正常,因而其治疗和预后又与急性心肌梗死有很大的差别。此外该病急性期有死亡风险,故应引起临床上的高度重视。近10余年来随着世界各地病例报告的不断增多,对Tako-Tsubo心肌病的研究也逐渐深入。现就其流行病学、发病机制、临床表现、诊断与治疗进行阐述,希望引起急诊科和心内科医生的关注。
Tako-Tsubo cardiomyopathy, also known as stress cardiomyopathy, sad syndrome, left ventricular apex balloon syndrome, transient left ventricular apex spherical changes. First reported by Japanese scholars, its clinical manifestations and acute myocardial infarction are very similar, including chest pain, ECG ST-T changes, left ventricular dysfunction, but its biggest difference with acute myocardial infarction is that its left ventricular dysfunction is reversible , And coronary angiography results more normal, so its treatment and prognosis and acute myocardial infarction are very different. In addition, the risk of death in the acute phase of the disease, it should cause clinical attention. In the past 10 years, with the increasing number of case reports from all over the world, the research on Tako-Tsubo cardiomyopathy has been gradually deepened. Now on its epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment are described, hoping to cause emergency department and cardiologist attention.