the personnel files of cadres in the disease control system are formed in the personnel management. They are documents and materials that record the cadres” undefined working experience and performance in various aspectsand the credentials for evaluating and understanding the cadres, which are related to many problems such as appointment, promotion and so on. At present, the concept of disease control system management has become more and more perfect, and the management of cadre personnel files has become more and more important. It is the basis of personnel management, so doing a good job in the management of personnel files of cadres in the disease control system is the premise where the disease control system works smoothly under the new situation.