论文部分内容阅读
[目的]探讨原发性透明细胞型肝癌(PCCCL)经手术切除治疗后影响预后的因素。[方法]回顾性分析广西医科大学附属肿瘤医院1996年1月至2006年12月间收治的52例PCCCL手术切除患者的临床资料,并进行单因素和多因素分析。[结果]全组患者术后l、3、5年总生存率分别为80.8%、46.2%、38.5%。多因素分析提示患者预后与甲胎蛋白水平、是否发生血管浸润、肝硬化背景和有无包膜相关。[结论]肿瘤包膜形成、大血管侵犯、甲胎蛋白水平、肝硬化背景是影响PCCCL患者预后的危险因素。
[Objective] To investigate the prognostic factors of primary clear cell hepatocellular carcinoma (PCCCL) after surgical resection. [Methods] The clinical data of 52 patients with PCCCL surgically removed from January 1996 to December 2006 in Cancer Hospital of Guangxi Medical University were retrospectively analyzed. Univariate and multivariate analyzes were performed. [Results] The overall survival rates at 1, 3, and 5 years after operation in all patients were 80.8%, 46.2% and 38.5%, respectively. Multivariate analysis suggested that the prognosis of patients with alpha-fetoprotein levels, whether vascular invasion, cirrhosis and the presence of capsule-related. [Conclusion] Tumor capsule formation, macrovascular invasion, alpha-fetoprotein level and cirrhosis background are the risk factors affecting the prognosis of patients with PCCCL.