猴头菌(Hericium erinaceum)含有芳香化合物、脂肪酸、甾醇和多糖。其中一些芳香化合物对HeLa细胞株具有显著的细胞毒性,并能刺激神经生长因子合成。本次从其子实体中分离得到2个新化合物(1、2)和1个已知化合物(3)。新鲜的猴头菌子实体(1.3kg),用乙醚常温提取3次,历时2周。乙醚 Hericium erinaceum contains aromatic compounds, fatty acids, sterols and polysaccharides. Some of these aromatic compounds have significant cytotoxicity to HeLa cell lines and can stimulate nerve growth factor synthesis. Two new compounds (1, 2) and one known compound (3) were isolated from their fruiting bodies. The fresh Hericium erinaceus fruit body (1.3 kg) was extracted with ethyl ether at room temperature 3 times for 2 weeks. Ethyl ether