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目的探讨马来酸桂哌齐特联用苦碟子对急性脑梗死的临床疗效。方法将83例急性脑梗死患者随机分为治疗组和对照组,对照组予控制脑水肿、脑保护及抗血小板聚集等常规治疗,治疗组在此基础上联用马来酸桂哌齐特注和苦碟子注射液,以14d为一个疗程,比较两组疗效。结果治疗组总有效率达93%,明显高于对照组的77.5%,两组比较差异显著(P<0.05),且无明显不良反应。结论马来酸桂哌齐特联用苦碟子对急性脑梗死临床疗效确切,安全性较好。
Objective To investigate the clinical efficacy of Cinepazide Maleate Kudie on acute cerebral infarction. Methods Eighty-three patients with acute cerebral infarction were randomly divided into treatment group and control group. The control group was given routine treatment of cerebral edema, cerebral protection and anti-platelet aggregation. The treatment group was treated with cinepazide maleate Kudie injection, to 14d for a course of treatment, the two groups were compared. Results The total effective rate in the treatment group was 93%, which was significantly higher than that in the control group (77.5%). There was significant difference between the two groups (P <0.05) and no obvious adverse reactions. Conclusion The cinepazide maleate Kudiezi is effective and safe in acute cerebral infarction.